Article
Ex vivo comparison of microbicide efficacies for preventing HIV-1 genomic integration in intraepithelial vaginal cells.
Antimicrobial agents and chemotherapy - 1 Feb 2010
McElrath M Juliana, Ballweber Lamar, Terker Andrew, Kreger Allison, Sakchalathorn Polachai, Robinson Barry, Fialkow Michael, Lentz Gretchen, Hladik Florian
Abstract excerpt
Vaginally applied microbicides hold promise as a strategy to prevent sexual HIV transmission. Several nonspecific microbicides, including the polyanion cellulose sulfate, have been evaluated in large-scale clinical trials but have failed to show significant efficacy. These findings have prompted...
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