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Article

Vitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontin.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2010

Li Xianwu, Speer Mei Y, Yang Hsueh, Bergen Jamie, Giachelli Cecilia M

Abstract excerpt

OBJECTIVE: Vascular calcification is highly correlated with morbidity and mortality, and it is often associated with inflammation. Vitamin D may regulate vascular calcification and has been associated with cardiovascular survival benefits. METHODS AND RESULTS: We developed a macrophage/smooth mus...

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Identifiers

PMID: 19948844
DOI: 10.1161/ATVBAHA.109.196576
PMCID: PMC2809826

Genes

BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19948844-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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