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Article

The metabolism of host RNAs in cells infected by an adenovirus E4 mutant.

Virology - 1 Mar 1991

Sandler A B, Ketner G

Abstract excerpt

Mutants of adenovirus type 5 (Ad5) that lack early region 4 (E4) are defective in the expression of viral late genes. E4 mutants exhibit dramatically reduced levels of both cytoplasmic and nuclear viral late RNAs compared to wild-type virus, due principally to reduced stability of unprocessed viral late RNA in the nucleus of mutant-infected cells. To determine whether E4 products also affect the metabolism of...

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Identifiers

PMID: 1994580
DOI: 10.1016/0042-6822(91)90498-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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