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Article

Exceptional molecular and coreceptor-requirement properties of molecular clones isolated from an Human Immunodeficiency Virus Type-1 subtype C infection.

Retrovirology - 7 Mar 2008

Dash Prasanta K, Siddappa Nagadenahalli B, Mangaiarkarasi Asokan, Mahendarkar Aruna V, Roshan Padmanabhan, Anand Krishnamurthy Kumar, Mahadevan Anita, Satishchandra Parthasarathy, Shankar Susarla K, Prasad Vinayaka R, Ranga Udaykumar

Abstract excerpt

BACKGROUND: The pathogenic significance of coreceptor switch in the viral infection of HIV-1 is not completely understood. This situation is more complex in subtype C infection where coreceptor switch is either absent or extremely rare. To gain insights into the mechanisms that underlie coreceptor requirement of subtype C, we screened several primary viral isolates and identified a clinical sample that...

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Source

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Identifiers

PMID: 18328091
DOI: 10.1186/1742-4690-5-25
PMCID: PMC2292743

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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