Article
VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA.
Journal of thrombosis and haemostasis : JTH - 1 Feb 2010
Kondkar A A, Bray M S, Leal S M, Nagalla S, Liu D J, Jin Y, Dong J F, Ren Q, Whiteheart S W, Shaw C, Bray P F
Abstract excerpt
BACKGROUND: Variation in platelet reactivity contributes to disorders of hemostasis and thrombosis, but the molecular mechanisms are not well understood. OBJECTIVES: To discover associations between interindividual platelet variability and the responsible platelet genes, and to begin to define the molecular mechanisms altering platelet gene expression. SUBJECTS/METHODS: Two hundred and eighty-eight healthy...
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