Article
Defining a role for Hfq in Gram-positive bacteria: evidence for Hfq-dependent antisense regulation in Listeria monocytogenes.
Nucleic acids research - 1 Jan 2010
Nielsen Jesper Sejrup, Lei Lisbeth Kristensen, Ebersbach Tine, Olsen Anders Steno, Klitgaard Janne Kudsk, Valentin-Hansen Poul, Kallipolitis Birgitte Haahr
Abstract excerpt
Small trans-encoded RNAs (sRNAs) modulate the translation and decay of mRNAs in bacteria. In Gram-negative species, antisense regulation by trans-encoded sRNAs relies on the Sm-like protein Hfq. In contrast to this, Hfq is dispensable for sRNA-mediated riboregulation in the Gram-positive species studied thus far. Here, we provide evidence for Hfq-dependent translational repression in the Gram-positive human...
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