Article
Definitive evidence that a single N-glycan among three glycans on inducible costimulator is required for proper protein trafficking and ligand binding.
Biochemical and biophysical research communications - 1 Jan 2010
Kamei Naoki, Fukui Rie, Suzuki Yoshiyuki, Kajihara Yasuhiro, Kinoshita Mitsuhiro, Kakehi Kazuaki, Hojo Hironobu, Tezuka Katsunari, Tsuji Takashi
Abstract excerpt
Glycosylation is a widespread post-translational modification found in glycoproteins. Glycans play key roles in protein folding, quality control in the endoplasmic reticulum (ER) and protein trafficking within cells. However, it remains unclear whether all positions of protein glycosylation are i...
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