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Article

Contribution of N-linked glycans to the conformation and function of intercellular adhesion molecules (ICAMs).

The Journal of biological chemistry - 18 Feb 2005

Jiménez David, Roda-Navarro Pedro, Springer Timothy A, Casasnovas José M

Abstract excerpt

The crystal structures of the glycosylated N-terminal two domains of ICAM-1 and ICAM-2 provided a framework for understanding the role of glycosylation in the structure and function of intercellular adhesion molecules (ICAMs). The most conserved glycans were less flexible in the structures, interacting with protein residues and contributing to receptor folding and expression. The first N-linked glycan in ICAM-2...

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PMID: 15545280
DOI: 10.1074/jbc.M412104200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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