Article
A novel genetic variant of BMP2K contributes to high myopia.
Journal of clinical laboratory analysis - 1 Jan 2009
Liu Hsin-Ping, Lin Ying-Ju, Lin Wei-Yong, Wan Lei, Sheu Jim Jinn-Chyuan, Lin Hui-Ju, Tsai Yuhsin, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
Loss of eye growth regulation may cause myopia, because modulation of optic globe size is essential for the generation of normal optic power. Evidence has implied variations of BMP2 gene expression mediate ocular development and retinal tissue remodeling. Given BMP2 as a potential regulator involved in myopia development, we investigate whether gene BMP2-inducible kinase (BMP2K, BIKe), whose expression is...
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