Article
HDL cholesterol response to GH replacement is associated with common cholesteryl ester transfer protein gene variation (-629C>A) and modified by glucocorticoid treatment.
European journal of endocrinology - 1 Feb 2010
Dullaart Robin P F, van den Berg Gerrit, van der Knaap Aafke M, Dijck-Brouwer Janneke, Dallinga-Thie Geesje M, Zelissen Peter M J, Sluiter Wim J, van Beek André P
Abstract excerpt
OBJECTIVE: GH replacement lowers total cholesterol and low-density lipoprotein cholesterol (LDL-C) in GH-deficient adults, but effects on high-density lipoprotein (HDL) cholesterol (HDL-C) are variable. Both GH and glucocorticoids decrease cholesteryl ester transfer protein (CETP) activity, which...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.