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Article

Propagation of Human Spermatogonial Stem Cells In Vitro

17 Nov 2009

Abstract excerpt

CONTEXT: Young boys treated with high-dose chemotherapy are often confronted with infertility once they reach adulthood. Cryopreserving testicular tissue before chemotherapy and autotransplantation of spermatogonial stem cells at a later stage could theoretically allow for restoration of fertility. OBJECTIVE: To establish in vitro propagation of human spermatogonial stem cells from small testicular biopsies to...

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Identifiers

PMID: 19920237
DOI: 10.1001/jama.2009.1689

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