Article
Role of oncogenic pathways and KRAS/BRAF mutations in the behavior of colon adenocarcinoma in renal transplant patients.
Transplantation - 15 Mar 2012
Revuelta Ignacio, Moya-Rull Daniel, García-Herrera Adriana, Rovira Jordi, Ayala de la Peña Francisco, Misiego Antonio, Guzmán Flavia, Oppenheimer Federico, Albanell Joan, Campistol Josep M
Abstract excerpt
BACKGROUND: The behavior and mechanisms of colorectal carcinoma in solid organ transplantation have not been well characterized. Our aim was to determine the clinical and molecular phenotypes of colorectal carcinoma in kidney transplant recipients and compare with those in the nonimmunosuppressed population. For the first time, we analyzed the impact of KRAS and BRAF mutations in kidney transplantation. METHODS:...
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