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Article

Asymmetric microtubule function is an essential requirement for polarized organization of the Drosophila bristle.

Molecular and cellular biology - 1 Jan 2010

Bitan Amir, Guild Gregory M, Bar-Dubin Dikla, Abdu Uri

Abstract excerpt

While previous studies have shown that microtubules (MTs) are essential for maintaining the highly biased axial growth of the Drosophila bristle, the mechanism for this process has remained vague. We report that the MT minus-end marker, Nod-KHC, accumulates at the bristle tip, suggesting that the MT network in the bristle is organized minus end out. Potential markers for studying the importance of properly...

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Identifiers

PMID: 19917727
DOI: 10.1128/MCB.00861-09
PMCID: PMC2798467

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