Article
The Drosophila javelin gene encodes a novel actin-associated protein required for actin assembly in the bristle.
Molecular and cellular biology - 1 Nov 2011
Shapira Shira, Bakhrat Anna, Bitan Amir, Abdu Uri
Abstract excerpt
The Drosophila melanogaster bristle is a highly polarized cell that builds specialized cytoskeletal structures. Whereas actin is required for increasing bristle length, microtubules are essential for bristle axial growth. To identify new proteins involved in cytoskeleton organization during bristle development, we focused on identifying and characterizing the javelin (jv) locus. We found that in a jv mutant, the...
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