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Article

Suppression of the defects in rdgB mutants of Escherichia coli K-12 by the cloned purA gene.

Journal of bacteriology - 1 Feb 1991

Clyman J, Cunningham R P

Abstract excerpt

A gene suppressing the defects of Escherichia coli rdgB (recA-dependent growth) and recA(Ts) rdgB mutants was cloned. The cloned gene suppresses the hyper-Rec phenotype and the enhanced level of SOS functions in rdgB mutants at the nonpermissive temperature. We identified the cloned gene as purA.

Topics

Cloning, Molecular
Electrophoresis, Polyacrylamide Gel
Escherichia coli
Genes, Bacterial
Genes, Suppressor
Kinetics
Mutation
Phenotype
Rec A Recombinases
Recombination, Genetic
Restriction Mapping
SOS Response, Genetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Temperature

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Identifiers

PMID: 1991730
DOI: 10.1128/jb.173.3.1360-1362.1991
PMCID: PMC207266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1991730-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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