Article
Phenotyping of an in vitro model of ischemic penumbra by iTRAQ-based shotgun quantitative proteomics.
Journal of proteome research - 1 Jan 2010
Datta Arnab, Park Jung Eun, Li Xin, Zhang Huoming, Ho Zhi Shan, Heese Klaus, Lim Sai Kiang, Tam James P, Sze Siu Kwan
Abstract excerpt
Cerebral ischemia is a major cause of death and long-term disability worldwide. Ischemic penumbra, the electrically silent but metabolically viable perifocal brain tissue, is the target for the much elusive stroke therapy. To characterize the molecular events of the dynamic penumbra, we applied a...
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