Article
Residue-specific analysis of frustration in the folding landscape of repeat beta/alpha protein apoflavodoxin.
Journal of molecular biology - 12 Feb 2010
Stagg Loren, Samiotakis Antonios, Homouz Dirar, Cheung Margaret S, Wittung-Stafshede Pernilla
Abstract excerpt
Flavodoxin adopts the common repeat beta/alpha topology and folds in a complex kinetic reaction with intermediates. To better understand this reaction, we analyzed a set of Desulfovibrio desulfuricans apoflavodoxin variants with point mutations in most secondary structure elements by in vitro and...
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