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Article

Apolipoprotein E genotype modifies the association between midlife lung function and cognitive function in old age.

Dementia and geriatric cognitive disorders - 1 Jan 2009

Giltay Erik J, Nissinen Aulikki, Giampaoli Simona, Kromhout Daan

Abstract excerpt

BACKGROUND/AIMS: Because poor lung function may be a risk factor for cognitive decline, we aimed to test the association of respiratory function with cognitive function and dementia later in life, as well as potential effect modification by APOE epsilon4 carrier status. METHODS: In a prospective population-based cohort study, forced vital capacity and forced expiratory flow were measured around 1965 in 857 men...

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Identifiers

PMID: 19907180
DOI: 10.1159/000255600
PMCID: PMC2853583

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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