Article
Large-scale reverse genetics in Arabidopsis: case studies from the Chloroplast 2010 Project.
Plant physiology - 1 Feb 2010
Ajjawi Imad, Lu Yan, Savage Linda J, Bell Shannon M, Last Robert L
Abstract excerpt
Traditionally, phenotype-driven forward genetic plant mutant studies have been among the most successful approaches to revealing the roles of genes and their products and elucidating biochemical, developmental, and signaling pathways. A limitation is that it is time consuming, and sometimes technically challenging, to discover the gene responsible for a phenotype by map-based cloning or discovery of the insertion...
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