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Enhanced detection and study of murine norovirus-1 using a more efficient microglial cell line

10 Nov 2009

Abstract excerpt

BACKGROUND: Human Noroviruses are the predominant cause of non-bacterial gastroenteritis worldwide. To facilitate prevention and control, a norovirus isolated from mice can provide a model to understand human noroviruses. To establish optimal viral infectivity conditions for murine noroviruses, several cell lines of hematopoietic lineage, including murine BV-2, RAW 264.7, and TIB, as well as human CHME-5, were...

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PMID: 19903359
DOI: 10.1186/1743-422x-6-196

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