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Establishment of an immortalized renal epithelial cell line derived from grass carp and its susceptibility to grass carp Reovirus genotype II.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology - 1 Jan 2026

Guo Xiudong, Zheng Shucheng, Yin Jiyuan, Li Yingying, Ren Yan, Mo Xubing, Zeng Weiwei, Zhang Liping, Mu Xidong, Wang Qing, Wang Yingying

Abstract excerpt

Hemorrhagic disease in grass carp (Ctenopharyngodon idella) caused by grass carp reovirus genotype II (GCRV-II) threatens sustainable aquaculture. To facilitate virus isolation, characterization, and studies on the pathogenic mechanisms of GCRV-II, we established a new cell line, Ctenopharyngodon idella trunk kidney (CITK). This cell line was developed using a trypsin digestion method and exhibited optimal...

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PMID: 41506315
DOI: 10.1016/j.cbpb.2026.111201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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