The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases.

doi:10.1128/mcb.11.2.822-832.1991

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Article

The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases.

Molecular and cellular biology - 1 Feb 1991

Coschigano P W, Magasanik B

Abstract excerpt

The URE2 gene of Saccharomyces cerevisiae has been cloned and sequenced. It encodes a predicted polypeptide of 354 amino acids with a molecular weight of 40,226. Deletion of the first 63 amino acids does not have any effect on the function of the protein. Studies with disruption alleles of the URE2 and GLN3 genes showed that both genes regulate GLN1 and GDH2, the structural genes for glutamine synthetase and...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
DNA, Fungal
Escherichia coli
Fungal Proteins
Genes, Fungal
Genetic Complementation Test
Genotype
Glutathione Peroxidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glutathione Transferase

Humans

Molecular Sequence Data

Nitrogen

Plasmids

Prions

Restriction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 1990286
DOI: 10.1128/mcb.11.2.822-832.1991
PMCID: PMC359734

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1990286-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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