Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct isolation in eggs of influenza A (H1N1) and B viruses with haemagglutinins of different antigenic and amino acid composition.

The Journal of general virology - 1 Jan 1991

Oxford J S, Newman R, Corcoran T, Bootman J, Major D, Yates P, Robertson J, Schild G C

Abstract excerpt

Influenza A (H1N1) and influenza B viruses from clinical samples were isolated in the amniotic cavity of embryonated hens' eggs by classical techniques and propagated in the allantoic cavity. Virus progeny from different eggs which had been inoculated with virus material from the same clinical sample possessed antigenically distinguishable haemagglutinins (HAs). Virus progeny of some eggs possessed HAs which were...

Topics

Amino Acid Sequence
Animals
Antigens, Viral
Cell Line
Chick Embryo
Hemagglutinins, Viral
Influenza A Virus, H1N1 Subtype
Influenza A virus
Influenza B virus
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Source

Identifiers

PMID: 1990062
DOI: 10.1099/0022-1317-72-1-185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1990062-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct isolation in eggs of influenza A (H1N1) and B viruses with haemagglutinins of different antigenic and amino acid composition.PMID 1990062Read ↗

Comparison of 10 influenza A (H1N1 and H3N2) haemagglutinin sequences obtained directly from clinical specimens to those of MDCK cell- and egg-grown virusesSemantic proximity Read ↗

Sequence analysis of the haemagglutinin (HA) of influenza A (H1N1) viruses present in clinical material and comparison with the HA of laboratory-derived virus.Semantic proximity Read ↗

The haemagglutinins of influenza A (H1N1) viruses in the 'O' or 'D' phases exhibit biological and antigenic differences.Semantic proximity Read ↗

Direct sequencing of the HA gene of influenza (H3N2) virus in original clinical samples reveals sequence identity with mammalian cell-grown virusSemantic proximity Read ↗

Receptor Specificity of Influenza A H3N2 Viruses Isolated in Mammalian Cells and Embryonated Chicken EggsSemantic proximity Read ↗

Amino acid sequence identity between the HA1 of influenza A (H3N2) viruses grown in mammalian and primary chick kidney cells.Semantic proximity Read ↗

Egg fluids and cells of the chorioallantoic membrane of embryonated chicken eggs can select different variants of influenza A (H3N2) viruses.Semantic proximity Read ↗

Molecular changes associated with adaptation of human influenza A virus in embryonated chicken eggs.Semantic proximity Read ↗

Comparison of antigenic mutation during egg and cell passage cultivation of H3N2 influenza virusSemantic proximity Read ↗

N-glycan profiles in H9N2 avian influenza viruses from chicken eggs and human embryonic lung fibroblast cellsSemantic proximity Read ↗

Performance characteristics of qualified cell lines for isolation and propagation of influenza viruses for vaccine manufacturingSemantic proximity Read ↗

Protein mutations following adaptation of avian influenza viruses in different biological systems.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.