Article
The haemagglutinins of influenza A (H1N1) viruses in the 'O' or 'D' phases exhibit biological and antigenic differences.
Epidemiology and infection - 1 Aug 1993
Azzi A, Bartolomei-Corsi O, Zakrzewska K, Corcoran T, Newman R, Robertson J S, Yates P, Oxford J S
Abstract excerpt
Influenza A (H1N1) viruses when initially isolated in mammalian cell cultures (MDCK cells) had different agglutination reactions with chicken and guinea-pig erythrocytes compared to the same viruses after passage. On first isolation the virus HA resembled the 'O' phase viruses described originally by Burnet and Bull and agglutinated mammalian but not avian erythrocytes. After passage, the virus HA resembled a...
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