Article
Combining DNA pooling with selective recombinant genotyping for increased efficiency in fine mapping.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Feb 2010
Chi Xiao-Fei, Lou Xiang-Yang, Shu Qing-Yao
Abstract excerpt
One of the key steps in positional cloning and marker-aided selection is to identify marker(s) tightly linked to the target gene (i.e., fine mapping). Selective genotyping such as selective recombinant genotyping (SRG) is commonly used in fine mapping for cost-saving. To further decrease genotyping effort and rapidly screen for tightly linked markers, we propose here a combined DNA pooling and SRG strategy. A...
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