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Article

Overexpression of Hr links excessive induction of Wnt signaling to Marie Unna hereditary hypotrichosis.

Human molecular genetics - 1 Feb 2010

Kim Jeong-Ki, Kim Eunmin, Baek In-Cheol, Kim Bong-Kyu, Cho A-Ri, Kim Tae-Yoon, Song Chang-Woo, Seong Je Kyung, Yoon Jong-Bok, Stenn Kurt S, Parimoo Satish, Yoon Sungjoo Kim

Abstract excerpt

Marie Unna hereditary hypotrichosis (MUHH) is a rare autosomal dominant hair disorder. Through the study of a mouse model, we identified a mutation in the 5'-untranslated region of the hairless (HR) gene in patients with MUHH in a Caucasian family. The corresponding mutation, named 'hairpoor', was found in mutant mice that were generated through N-ethyl-N-nitrosourea mutagenesis. Hairpoor mouse mutants display...

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Identifiers

PMID: 19897589
DOI: 10.1093/hmg/ddp509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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