Article
Overexpression of cell division cycle 7 homolog is associated with gene amplification frequency in breast cancer.
Human pathology - 1 Mar 2010
Choschzick Matthias, Lebeau Annette, Marx Andreas H, Tharun Lars, Terracciano Luigi, Heilenkötter Uwe, Jaenicke Fritz, Bokemeyer Carsten, Simon Ronald, Sauter Guido, Schwarz Jörg
Abstract excerpt
Cell division cycle 7 is a widely expressed protein kinase implicated in cell division, cell cycle checkpoint mechanisms, and cancer progression. To determine the relationship of cell division cycle 7 protein expression with tumor phenotype, molecular features and prognosis, 2197 highly characterized breast carcinomas were analyzed on a tissue microarray. Detectable cell division cycle 7 expression was found in...
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