Article
Comparisons of telomere lengths in peripheral blood and cerebellum in Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Nov 2009
Lukens J Nicholas, Van Deerlin Vivianna, Clark Christopher M, Xie Sharon X, Johnson F Brad
Abstract excerpt
BACKGROUND: Alzheimer's disease (AD) patients have been reported to have shorter telomeres in peripheral blood leukocytes (PBLs) than age-matched control subjects. However, it is unclear if PBL telomere length reflects brain telomere length, which might play a more direct role in AD pathogenesis. We examined the correlation between PBL and cerebellum telomere length in AD patients, and compared telomere lengths...
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