Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The nature of fibrous dysplasia.

Head & face medicine - 9 Nov 2009

Feller Liviu, Wood Neil H, Khammissa Razia A G, Lemmer Johan, Raubenheimer Erich J

Abstract excerpt

Fibrous dysplasia has been regarded as a developmental skeletal disorder characterized by replacement of normal bone with benign cellular fibrous connective tissue. It has now become evident that fibrous dysplasia is a genetic disease caused by somatic activating mutation of the Gsalpha subunit of G protein-coupled receptor resulting in upregulation of cAMP. This leads to defects in differentiation of osteoblasts...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and treatments
Share to Bone Tumor Diagnosis and Treatments
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Oral and Maxillofacial Pathology

Share to Osteoblasts

Share to Radiography

Source

Open in PubMed Open full text

Identifiers

PMID: 19895712
DOI: 10.1186/1746-160X-5-22
PMCID: PMC2779176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The nature of fibrous dysplasia.PMID 19895712Read ↗

Fibrous dysplasia.Semantic proximity Read ↗

Cellular and molecular basis of fibrous dysplasia.Semantic proximity Read ↗

Current concepts of craniofacial fibrous dysplasia: pathophysiology and treatmentSemantic proximity Read ↗

Fibrous dysplasia.Semantic proximity Read ↗

Fibrous dysplasia of bone: craniofacial and dental implicationsSemantic proximity Read ↗

Fibrous dysplasia of the jaws: Integrating molecular pathogenesis with clinical, radiological, and histopathological featuresSemantic proximity Read ↗

The CREB–Smad6–Runx2 axis contributes to the impaired osteogenesis potential of bone marrow stromal cells in fibrous dysplasia of boneSemantic proximity Read ↗

Fibrous dysplasia/McCune-Albright syndrome: state-of-the-art advances, pathogenesis, and basic/translational researchSemantic proximity Read ↗

[Fibrous dysplasia of bone].Semantic proximity Read ↗

Transcriptomic Signature and Pro-Osteoclastic Secreted Factors of Abnormal Bone-Marrow Stromal Cells in Fibrous DysplasiaSemantic proximity Read ↗

Transcriptomic signature and pro-osteoclastic secreted factors of abnormal bone marrow stromal cells in fibrous dysplasiaSemantic proximity Read ↗

Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.