An inverse association between history of childhood eczema and subsequent risk of type 1 diabetes that is not likely to be explained by HLA-DQ, PTPN22, or CTLA4 polymorphisms.

doi:10.1111/j.1399-5448.2009.00605.x

Article

An inverse association between history of childhood eczema and subsequent risk of type 1 diabetes that is not likely to be explained by HLA-DQ, PTPN22, or CTLA4 polymorphisms.

Pediatric diabetes - 1 Sept 2010

Stene Lars C, Rønningen Kjersti S, Bjørnvold Marit, Undlien Dag E, Joner Geir

Abstract excerpt

BACKGROUND: Established genetic susceptibility loci for type 1 diabetes are important in immune regulation and may play a role also in atopic disorders, potentially explaining the inverse association between childhood eczema and subsequent risk for type 1 diabetes previously reported. OBJECTIVE:...

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An inverse association between history of childhood eczema and subsequent risk of type 1 diabetes that is not likely to be explained by HLA-DQ, PTPN22, or CTLA4 polymorphisms.

Abstract excerpt

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