Article
Forward mutation of S. typhimurium by smokeless tobacco extracts.
Mutation research - 1 Jan 1991
Shirnamé-Moré L
Abstract excerpt
Mutagenicity of 4 popular brands of smokeless tobaccos was studied using a S. typhimurium forward mutation assay. Aqueous extracts of 4 brands and dichloromethane and methanol extracts of 1 of the 4 brands of smokeless tobacco's did not induce significant mutagenicity either in the presence or absence of metabolic activation. Aqueous and organic extracts were however mutagenic when treated with physiological...
Topics
- Biotransformation
- Hydrogen-Ion Concentration
- Methanol
- Methylene Chloride
- Mutagenicity Tests
- Mutation
- Nitrosation
- Plant Extracts
- Plants, Toxic
- Salmonella typhimurium
- Sodium Nitrite
- Tobacco, Smokeless