Article
Forward mutation of S. typhimurium by smokeless tobacco extracts.
Mutation research - 1 Jan 1991
Shirnamé-Moré L
Abstract excerpt
Mutagenicity of 4 popular brands of smokeless tobaccos was studied using a S. typhimurium forward mutation assay. Aqueous extracts of 4 brands and dichloromethane and methanol extracts of 1 of the 4 brands of smokeless tobacco's did not induce significant mutagenicity either in the presence or absence of metabolic activation. Aqueous and organic extracts were however mutagenic when treated with physiological...
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