Article
Risk of gastric cancer is associated with the MUC1 568 A/G polymorphism.
International journal of oncology - 1 Dec 2009
Xu Qian, Yuan Yuan, Sun Li-Ping, Gong Yue-Hua, Xu Ying, Yu Xiu-Wen, Dong Nan-Nan, Lin G David, Smith Paul N, Li Rachel W
Abstract excerpt
Identifying the genetic variants that alter MUC1 protein expression may further our understanding of the risk for development of gastric cancer (GC). We used PCR-SSPs to identify the genotype of MUC1 A/G polymorphism at its 568 site of exon 2 and immunohistochemistry to detect MUC1 protein expression in GC patients and non-cancer subjects and analyzed the association between this polymorphism and MUC1 protein...
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