Article
Adequate use of allele frequencies in Hispanics--a problem elucidated in nephrotic syndrome.
Pediatric nephrology (Berlin, Germany) - 1 Feb 2010
Chernin Gil, Heeringa Saskia F, Vega-Warner Virginia, Schoeb Dominik S, Nürnberg Peter, Hildebrandt Friedhelm
Abstract excerpt
Previous studies in children with focal segmental glomerulosclerosis (FSGS) and nephrotic syndrome (NS) in the USA have revealed inter-ethnic differences in their clinical presentation and outcome. However, ethnicity was based on self-identification rather than on molecular genetic data. Here, we show that genetic heterogeneity exists in self-identified Hispanic (Spanish-American) patients with steroid-resistant...
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