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Article

delta-Aminolevulinic acid dehydratase deficiency can cause delta-aminolevulinate auxotrophy in Escherichia coli.

Journal of bacteriology - 1 Jan 1991

O'Neill G P, Thorbjarnardóttir S, Michelsen U, Pálsson S, Söll D, Eggertsson G

Abstract excerpt

Ethylmethane sulfonate-induced mutants of several Escherichia coli strains that required delta-aminolevulinic acid (ALA) for growth were isolated by penicillin enrichment or by selection for respiratory-defective strains resistant to the aminoglycoside antibiotic kanamycin. Three classes of mutants were obtained. Two-thirds of the strains were mutants in hemA. Representative of a third of the mutations was the...

Topics

Aminolevulinic Acid
Base Sequence
DNA, Bacterial
Escherichia coli
Ethyl Methanesulfonate
Genes, Bacterial
Genetic Complementation Test
Genotype
Molecular Sequence Data
Mutation
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Porphobilinogen Synthase

Transduction, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1987138
DOI: 10.1128/jb.173.1.94-100.1991
PMCID: PMC207161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1987138-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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