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Article

delta-Aminolevulinic acid dehydratase deficiency can cause delta-aminolevulinate auxotrophy in Escherichia coli.

Journal of bacteriology - 1 Jan 1991

O'Neill G P, Thorbjarnardóttir S, Michelsen U, Pálsson S, Söll D, Eggertsson G

Abstract excerpt

Ethylmethane sulfonate-induced mutants of several Escherichia coli strains that required delta-aminolevulinic acid (ALA) for growth were isolated by penicillin enrichment or by selection for respiratory-defective strains resistant to the aminoglycoside antibiotic kanamycin. Three classes of mutants were obtained. Two-thirds of the strains were mutants in hemA. Representative of a third of the mutations was the...

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Identifiers

PMID: 1987138
DOI: 10.1128/jb.173.1.94-100.1991
PMCID: PMC207161

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