Article
Cloning and characterization of genes involved in the biosynthesis of delta-aminolevulinic acid in Escherichia coli.
Gene - 2 Nov 1992
Ikemi M, Murakami K, Hashimoto M, Murooka Y
Abstract excerpt
Several mutants of Escherichia coli that had lost their ability to synthesize delta-aminolevulinic acid (ALA) via the C5 pathway were isolated. Their defective loci were classified into two groups, AlaA- and AlaB-. The genes that complemented these mutations were cloned. Nucleotide sequencing indicated that the gene that complemented AlaA- was identical to hemL which is located at 4 min on the E. coli chromosome...
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