Article
Hereditary gynaecological malignancies: advances in screening and treatment.
Histopathology - 1 Jan 2013
Folkins Ann K, Longacre Teri A
Abstract excerpt
In the last two decades there have been significant advances in our understanding of female genital tract tumours. The discovery of BRCA1 and BRCA2 genes in ovarian cancer and the mismatch repair genes in endometrial carcinoma has revolutionized our approach to the diagnosis and screening of women for ovarian and uterine cancers. This review discusses the pathogenesis of these two hereditary syndromes in depth...
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