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Cancer stem cells: a reality, a myth, a fuzzy concept or a misnomer? An analysis

25 Oct 2009

Abstract excerpt

The concept of cancer stem cells (CSC) embodies two aspects: the stem cell as the initial target of the oncogenic process and the existence of two populations of cells in cancers: the CSC and derived cells. The second is discussed in this review. CSC are defined as cells having three properties: a selectively endowed tumorigenic capacity, an ability to recreate the full repertoire of cancer cells of the parent...

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PMID: 19858069
DOI: 10.1093/carcin/bgp259

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