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Cancer stem cell and cancer stemloids: From biology to therapy

1 Nov 2007

Abstract excerpt

It has become a cliché that cancer therapy fails because it does not target rare cancer stem cells (CSCs). Here we are discuss that this is not how therapy fails and not any cancer cell with stem-like properties is CSC. Paradoxically, CSCs must be resting to explain their resistance to therapy yet must be cycling to explain their persistence in cell culture. To solve contradictions, this article introduces the...

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PMID: 18344680
DOI: 10.4161/cbt.6.11.5167

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