Article
Digit ratios do not serve as anatomical evidence of prenatal androgen exposure in clinical phenotypes of polycystic ovary syndrome.
Human reproduction (Oxford, England) - 1 Jan 2010
Lujan Marla E, Bloski Terri G, Chizen Donna R, Lehotay Denis C, Pierson Roger A
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) is heterogeneous in its clinical presentation and four major phenotypes have been identified. The precise etiology of PCOS is unknown; however, variable exposure to prenatal androgens may be responsible for the spectrum of endocrine and metabolic disturbances characteristic of this syndrome. Since prenatal testosterone exposure is known to decrease the ratio of the...
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