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Article

Biological basis of rabies virus neurovirulence in mice: comparative pathogenesis study using the immunoperoxidase technique.

Journal of virology - 1 Jan 1991

Jackson A C

Abstract excerpt

The CVS strain of fixed rabies virus causes acute, fatal encephalomyelitis in young adult ICR mice. Variant RV194-2, which was selected from CVS virus in cell culture with a neutralizing antiglycoprotein monoclonal antibody, has a single amino acid change in the glycoprotein. The infections caused by CVS virus and RV194-2 virus were compared in mice for 14 days postinoculation of 5 x 10(7) PFU into the right...

Topics

Animals
Antibodies, Monoclonal
Antigens, Viral
Cerebellum
Encephalomyelitis
Genetic Variation
Mice
Mice, Inbred ICR
Purkinje Cells
Rabies virus
Species Specificity
Virulence

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Identifiers

PMID: 1985216
DOI: 10.1128/JVI.65.1.537-540.1991
PMCID: PMC240553

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1985216-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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