Article
One Hundred Years of Congenital Fibrinogen Disorders.
Seminars in thrombosis and hemostasis - 1 Nov 2022
Casini Alessandro, Moerloose Philippe de, Neerman-Arbez Marguerite
Abstract excerpt
Congenital fibrinogen disorders encompass a broad range of fibrinogen defects characterized by a wide molecular and clinical spectrum. From the first clinical description of afibrinogenemia in 1920, many major achievements have contributed to a better understanding of these complex disorders. The finding of causative mutations in all three fibrinogen genes has contributed to reveal the molecular mechanisms...
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