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Article

Genetic heterogeneity of group A rotaviruses: a review of the evolutionary dynamics and implication on vaccination.

Expert review of anti-infective therapy - 1 Dec 2022

Omatola Cornelius A, Olaniran Ademola O

Abstract excerpt

INTRODUCTION: Human rotavirus remains a major etiology of acute gastroenteritis among under 5-year children worldwide despite the availability of oral vaccines. The genetic instability of rotavirus and the ability to form different combinations from the different G- and P-types reshapes the antigenic landscape of emerging strains which often display limited or no antigen identities with the vaccine strain. As...

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Identifiers

PMID: 36285575
DOI: 10.1080/14787210.2022.2139239

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