Article
Genetic and antigenic diversity of human rotaviruses: potential impact on vaccination programs.
The Journal of infectious diseases - 1 Sept 2010
Kirkwood Carl D
Abstract excerpt
The successful development and implementation of rotavirus vaccines will have a significant impact on rotavirus-induced gastroenteritis in children worldwide. However, this introduction will increase the immune pressure against wild-type rotavirus strains circulating in the community, altering the forces and balances that drive rotavirus evolution. There is concern that antigenically distinct novel or rare...
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