Article
Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs.
The Journal of infectious diseases - 1 Sept 2005
Gentsch Jon R, Laird Ashley R, Bielfelt Brittany, Griffin Dixie D, Banyai Krisztian, Ramachandran Madhu, Jain Vivek, Cunliffe Nigel A, Nakagomi Osamu, Kirkwood Carl D, Fischer Thea K, Parashar Umesh D, Bresee Joseph S, Jiang Baoming, Glass Roger I
Abstract excerpt
The development of rotavirus vaccines that are based on heterotypic or serotype-specific immunity has prompted many countries to establish programs to assess the disease burden associated with rotavirus infection and the distribution of rotavirus strains. Strain surveillance helps to determine whether the most prevalent local strains are likely to be covered by the serotype antigens found in current vaccines....
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