Article
Preliminary results on cystic fibrosis haplotypes from patients diagnosed in Odessa.
Acta Universitatis Carolinae. Medica - 1 Jan 1990
De Benedetti L, Ronchetto P, Devoto M, Romeo G, Krainiaia G V, Reznik B Y
Abstract excerpt
Two RFLP's closely linked to the CF gene (KM.19/PstI and XV-2c/TaqI) have been analysed in a sample of CF families in which one or more affected children had been diagnosed by the CF Centre of Odessa. The most frequent haplotype in CF chromosomes (2-1) is the same observed with higher frequency in other populations. If confirmed on a larger sample of CF patients from the USSR, this result might be indicative of...
Topics
- Alleles
- Child
- Cystic Fibrosis
- Gene Frequency
- Haplotypes
- Humans
- Mutation
- Polymorphism, Restriction Fragment Length