Genetic differences in cystic fibrosis patients with and without pancreatic insufficiency. An Italian collaborative study.

doi:10.1007/BF00195815

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Article

Genetic differences in cystic fibrosis patients with and without pancreatic insufficiency. An Italian collaborative study.

Human genetics - 1 Apr 1990

Ferrari M, Antonelli M, Bellini F, Borgo G, Castiglione O, Curcio L, Dallapiccola B, Devoto M, Estivill X, Gasparini P

Abstract excerpt

To determine the number and frequency of mutations that occur at the cystic fibrosis locus (CF), we have examined the allele and haplotype frequencies of eight polymorphic DNA markers linked to CF in 163 Italian patients who were sub-divided according to their clinical presentations. The distribu...

Topics

Alleles
Child
Child, Preschool
Cystic Fibrosis
DNA Probes
Exocrine Pancreatic Insufficiency
Gene Frequency
Genetic Variation
Haplotypes
Humans
Infant

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