Article
Studies of RFLP closely linked to the cystic fibrosis locus throughout Europe lead to new considerations in populations genetics.
Human genetics - 1 Apr 1990
Serre J L, Simon-Bouy B, Mornet E, Jaume-Roig B, Balassopoulou A, Schwartz M, Taillandier A, Boué J, Boué A
Abstract excerpt
The prenatal diagnosis of cystic fibrosis is now routinely performed by using two probes tightly linked to the CF locus (XV2C and KM19). These probes have been shown to exhibit a strong linkage disequilibrium with the CF locus. Our data (103 families) have been pooled with other French data (237...
Topics
- Cystic Fibrosis
- Europe
- Fetal Diseases
- Gene Frequency
- Genetics, Population
- Humans
- Models, Genetic
- Mutation
- Polymorphism, Restriction Fragment Length
- Prenatal Diagnosis