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Article

Human papillomavirus-16 E7 interacts with glutathione S-transferase P1 and enhances its role in cell survival.

PloS one - 13 Oct 2009

Mileo Anna M, Abbruzzese Claudia, Mattarocci Stefano, Bellacchio Emanuele, Pisano Paola, Federico Antonio, Maresca Vittoria, Picardo Mauro, Giorgi Alessandra, Maras Bruno, Schininà M Eugenia, Paggi Marco G

Abstract excerpt

BACKGROUND: Human Papillomavirus (HPV)-16 is a paradigm for "high-risk" HPVs, the causative agents of virtually all cervical carcinomas. HPV E6 and E7 viral genes are usually expressed in these tumors, suggesting key roles for their gene products, the E6 and E7 oncoproteins, in inducing malignant transformation. METHODOLOGY/PRINCIPAL FINDINGS: By protein-protein interaction analysis, using mass spectrometry, we...

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Source

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Identifiers

PMID: 19826491
DOI: 10.1371/journal.pone.0007254
PMCID: PMC2758704

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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