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Side population cells have the characteristics of cancer stem-like cells/cancer-initiating cells in bone sarcomas

29 Sept 2009

Abstract excerpt

BACKGROUND: Several human cancers have been found to contain cancer stem-like cells (CSCs) having cancer-initiating ability. However, only a few reports have shown the existence of CSCs in bone and soft tissue sarcomas. In this study, we identified and characterised side population (SP) cells that showed drug-resistant features in human bone sarcoma cell lines. METHODS: In seven osteosarcoma cell lines (OS2000,...

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PMID: 19826427
DOI: 10.1038/sj.bjc.6605330

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