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Article

Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 2010

Huang Hechang, Chikazu Daichi, Voznesensky Olga S, Herschman Harvey R, Kream Barbara E, Drissi Hicham, Pilbeam Carol C

Abstract excerpt

Murine MC3T3-E1 and MC-4 cells were stably transfected with -371/+70 bp of the murine cyclooxygenase-2 (COX-2) promoter fused to a luciferase reporter (Pluc371) or with Pluc371 carrying site-directed mutations. Mutations were made in (1) the cAMP response element (CRE) at -57/-52 bp, (2) the acti...

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Identifiers

PMID: 19821778
DOI: 10.1359/jbmr.091019
PMCID: PMC3153333

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19821778-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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